Today, the production of science and knowledge is one of the indicators of civilization that has had a special place in the words of theorists of Islamic society after the Islamic revolution. The importance of science as a pillar of civilization is so far that the lack or deficiency of this pillar overshadows the respectability, independence, identity, security and well-being of the country. Therefore, Ayatollah Khamenei, the supreme leader of the revolution, in the last few years has been emphasizing more and more the importance of producing science and knowledge in empowering the society. Considering that the revision and reproduction of textbooks, i.e., the evolution of textbooks in educational centers, is considered one of the foundations of science production, in this article, with the qualitative method of content analysis, the evolution of textbooks with the civilizational perspective of Ayatollah Khamenei was analyzed and after going back and forth Among the themes and their analysis, 35 basic themes, eight organizing themes and finally three comprehensive themes were obtained. From Ayatollah Khamenei's point of view, the need to revise the textbooks was created in the form of three codes: "editing textbooks with a civilizational background", "problemization of textbooks" and "editing strategies". Also, "existence of exclusive view", "lack of attention to modern needs" and "weakness of expression of textbooks" play a role in creating the damage of current textbooks. By analyzing and combining the codes of compilation requirements, the transformation in "content requirements" and "appearance" was obtained. The findings, due to the fact that the categories are based on the content of the prominent scholars of contemporary seminaries and their adaptation to religious teachings and current issues, are not dependent only on the compilation of the texts of the seminaries of sisters and brothers, and the applicability in various situations, especially the planning and research organization of the country and the organization The publishing of university textbooks (Samt) has and can provide important indicators for drawing and formulating a revolutionary policy for the development of textbooks and improving the quality of the educational system.